Endotoxins are components of bacterial cell walls that are released during cell lysis and are the major by-products in recombinant proteins purified from E. coli. It is very stable to both pH and heat, making it difficult to remove during the protein purification process. Because endotoxins exist in a wide range and play an important role in biotherapeutic development, scientists have focused on developing unique methods to maintain endotoxin-free workflows.
Creative BioMart has introduced professional equipment and experienced technicians to establish a powerful endotoxin-free protein purification platform. We ensure that from starting material to finished product, your protein product is free of endotoxins introduced during purification. We can use a variety of techniques to remove endotoxins, including ultrafiltration, surfactants, activated carbon, anion exchange chromatography, immobilized Sepharose, etc. Using our improved and validated technology platform, endotoxins less than 0.005 EU/ml can be achieved. While effectively solving the yield and cost problems caused by these removal methods, it also greatly ensures the biological activity of the protein product.
As a leading expert in endotoxin research, Creative BioMart has the solid expertise and scientific background to provide strong technical support to researchers around the world. To fully assist our customers in obtaining low endotoxin proteins, we offer various high-quality purification kits to choose from. In addition, we provide systematic and efficient one-stop purification services to accelerate your research projects. If you are interested in our services, please contact us for more details. 0020
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