Endotoxins are toxic molecules present in microorganisms such as bacteria, fungi, and viruses. It is usually composed of lipopolysaccharide (LPS) and lipopeptide polysaccharide (Lipid A), which is considered to be one of the main pathogenic factors of many infectious diseases and widely exists in nature. Endotoxin activates the body's immune system by binding to Toll-like receptors (TLR) on host cells, causing a series of infectious diseases, such as meningitis, sepsis, and pneumonia. Therefore, the detection and removal of endotoxins contribute to the study of their pathogenicity and harm in the scientific field.
Figure 1. Illustration of the lipopolysaccharide biochemical structure existing in the outer membrane of gram-negative bacteria. (Su W, et al., 2015)
The impact of endotoxin on the body is extremely complex and is closely related to human health and disease. Therefore, the detection of endotoxin has very important theoretical value and clinical significance.
Creative BioMart offers you a variety of endotoxin services and related products. From kits, reagents to experimental consumables to endotoxin derivatives, we can provide comprehensive assistance for your experiments. You can quickly find the reagent you need by searching keywords such as CAT number or product name. Please tell us your product needs, we will provide you with a comprehensive consultation. If you have any questions, please feel free to contact us.
Reference