Plasmids play a vital role as molecular tools widely used for DNA manipulation and gene expression in various microbial and animal cells. Plasmids have many applications in biotechnology and are commonly used as cloning vectors in bacteria and for large-scale protein production, gene therapy, and mRNA therapy. Endotoxin is a unique component on the cell wall of Gram-negative bacteria. Due to its chemical structure and characteristics, it is easy to mix with the plasmid DNA and extract it together during the purification of the plasmid. The existence of endotoxin will cause cell death and seriously affect the efficiency of plasmid transfection cells, so it needs to be removed during the purification of plasmid DNA during the production of gene vaccines.
Figure 1. The illustration shows the structure of the cell with plasmids.
In addition to the Endotoxin-Free Plasmid Kit, we also provide endotoxin-free antibody purification kits for the purification of Protein A and Protein G.
Creative BioMart can offer a series of high-quality endotoxin-free purification kits for scientific research institutes and biotechnology research to meet experimental needs. In order to assist the majority of scientific researchers in their research on plasmid DNA, Creative BioMart, as a professional solution provider in the field of life sciences, recommends products related to plasmid DNA purification and endotoxin removal for you. You can quickly find the reagent you need by searching keywords such as CAT number or product name. Please tell us your product needs, we will provide you with a comprehensive consultation. If you have any questions, please feel free to contact us.
