Endotoxin Testing in Nucleic acid

Among infectious diseases, Gram-negative bacteria (GNB) infection has the highest clinical mortality rate for sepsis, endotoxemia, and shock. During GNB infection, bacteria and lipopolysaccharide enter the blood circulation, activate various inflammatory cells to release inflammatory mediators, cause inflammatory reactions, and in severe cases can lead to multiple organ failure. LPS is the main component of the GNB outer membrane. It consists of lipid A, core oligosaccharides and O-specific polysaccharide side chains. LPS plays a major role in maintaining GNB's outer membrane permeability and migration and its pathogenic process. LPS can also directly or indirectly induce the apoptosis of immune cells and suppress the body's immune function, thereby exacerbating the occurrence of sepsis. Therefore, the testing of lipopolysaccharide has important medical significance. Recent research shows that DNA and RNA not only play a role in storing and transmitting genetic information, but can also interact with other types of molecules through their own unique structures. Based on this, an artificially designed random oligonucleotide library can be established. This is also very important for detecting endotoxin in nucleic acids.

Endotoxin testing in nucleic acid

Creative BioMart provides a full range of services for endotoxin testing. Our endotoxin testing services cover a wide range of methods and are available for a wide range of samples to provide comprehensive and efficient help for your experiments. Creative BioMart' nucleic acid endotoxin testing service mainly uses chromogenic LAL analysis and Gel Clot LAL Assay.

Our Services for endotoxin testing in nucleic acid

Creative BioMart offers a corresponding endotoxin testing service. You can purchase the corresponding endotoxin removal kit and related accessory products according to the needs of your own samples. We guarantee that all instruments, water, reagents, and consumables used in the experiment are free of endotoxins, and the experiment is conducted in a clean room to ensure that low levels of endotoxins are returned to the sample. In addition, we can also provide you with related services including:

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Project name Endotoxin testing in nucleic acid
Testing purpose Gram-negative bacteria (GNB) infection has the highest clinical mortality rate for sepsis, endotoxemia, and shock. During GNB infection, bacteria and lipopolysaccharide enter the blood circulation, activate various inflammatory cells to release inflammatory mediators, cause inflammatory reactions, and in severe cases can lead to multiple organ failure.
Testing cycle 3-5 days.
Service including We provide you with raw data and test reports.
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