Low Endotoxin Cytokines
Introduction of Cytokines
Cytokines (CK) are small molecule polypeptides or glycoproteins synthesized and secreted by activated immune cells and non-immune cells that can regulate cell physiological functions, participate in immune response, and mediate inflammatory response and other biological effects. It is another class of immune molecules different from immunoglobulin and complement. The main function is to mediate and regulate immune response, participate in inflammatory response, promote cell proliferation and differentiation, and participate in hypersensitivity and autoimmune diseases. Cytokines are widely used in basic scientific research and drug development. Cytokines with higher purity, lower endotoxin, and better biological activity are more popular, among which low endotoxin cytokines are the most critical.
Figure 1. Role of major cytokines in the tumour microenvironment. (Seruga B, et al., 2008)
Endotoxin contamination of reagents is a potentially significant problem that can lead to erroneous conclusions in experiments. Endotoxin will affect the growth and function of cells, so low endotoxin cytokines are the first choice for scientific research.
Advantages of Our Products
- Low endotoxin, far below the industry average.
- High purity, high activity, high batch-to-batch consistency.
- Does not contain carrier protein.
- Rich in variety and wide in application.
- The product form is freeze-dried powder, which has better stability than liquid and is easier to store for a long time.
Applications of Our Products
- Organoids, stem cells, immune cells, and disease modeling
- High-standard cell culture medium preparation
- R&D and production of new drugs
- Cell culture experiments, cell therapy, cell apoptosis research, stem cell culture and expansion differentiation (IPS), and functional analysis
- As an antigen, it is used to produce high-quality antibodies.
- Used as a standard in ELISA and other analytical methods.
Creative BioMart is committed to providing a series of high-quality low endotoxin cytokines for scientific research institutes and biotechnology research to meet experimental needs. You can quickly find the reagent you need by searching keywords such as CAT number or product name. Please tell us your product needs, we will provide you with a comprehensive consultation. If you have any questions, please feel free to contact us.
Reference
- Seruga B, Zhang H, Bernstein L J, et al. (2008). Cytokines and their relationship to the symptoms and outcome of cancer[J]. Nature Reviews Cancer. 8(11): 887-899.
Origin:
Forms:
Storage: Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months.
Principle:
Origin:
Mouse
Forms:
Liquid (sterile filtered)
Storage: Store Mouse IgG control protein at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Principle:
Origin:
Rabbit
Forms:
Liquid (sterile filtered)
Storage: Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. Low Endotoxin Control Rabbit IgG is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
Principle:
