Cat#:	INH-001
Description/Features:	Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin with anti-inflammatory and anti-cancer properties. DMC suppresses cell proliferation, migration and invasion in cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits lipopolysaccharide induction of iNOS by blocking NF-κ activation. It also has been shown to inhibit energy metabolic and oncogenic signaling pathways through AMPK activation. In addition it is a potent inhibitor of P-Type ATPases. Shown to have neuroprotective properties. It also has anti-plasmodial activity.
Origin:	Plant
Forms:	Yellow to orange powder.
Purity:	≥98% (HPLC)
Formula:	C20H18O5
MW:	338.35
CAS:	22608-11-3
Solubility:	Soluble in DMSO (10mg/ml) or DMF (10mg/ml).
Identity:	Determined by 1H-NMR.
Synonyms:	DMC; (E,E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione; Desmethoxycurcumin; Monodemethoxycurcumin
Storage:	Protect from light and moisture. Stable for at least 2 years after receipt when stored at +4°C.