Cat# INH-001
Description/Features Demethoxycurcumin (DMC) is a natural demethoxy derivative of curcumin with anti-inflammatory and anti-cancer properties. DMC suppresses cell proliferation, migration and invasion in cancer cells. It down-regulates the transcriptional coactivator p300, suppressing the Wnt/β-catenin pathway, and inhibits lipopolysaccharide induction of iNOS by blocking NF-κ activation. It also has been shown to inhibit energy metabolic and oncogenic signaling pathways through AMPK activation. In addition it is a potent inhibitor of P-Type ATPases. Shown to have neuroprotective properties. It also has anti-plasmodial activity.
Origin Plant
Forms Yellow to orange powder.
Purity ≥98% (HPLC)
Formula C20H18O5
MW 338.35
CAS 22608-11-3
Solubility Soluble in DMSO (10mg/ml) or DMF (10mg/ml).
Identity Determined by 1H-NMR.
Synonyms DMC; (E,E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione; Desmethoxycurcumin; Monodemethoxycurcumin
Storage Protect from light and moisture. Stable for at least 2 years after receipt when stored at +4°C.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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