Wnt-3a is one of 19 vertebrate members of the Wingless-type MMTV integration site (Wnt) family of highly conserved cysteine-rich secreted glycoproteins important for normal developmental processes.Required for normal embryonic mesoderm development and formation of caudal somites. Required for normal morphogenesis of the developing neural tube (By similarity). Mediates self-renewal of the stem cells at the bottom on intestinal crypts (in vitro).
| Short Name: | Recombinant Human WNT3A V2 Protein, low endotoxin |
| Cat#: | EPLE-31H |
| Recombinant: | Human Cells |
| Abbr: | WNT3A(Human) |
| Alias: | WNT3A; wingless-type MMTV integration site family, member 3A; protein Wnt-3a; MGC119418; MGC119419; MGC119420; |
| Type: | W |
| similar: | WNT3A |
| Product Overview: | Recombinant Human Protein Wnt-3a is produced by our Mammalian expression system and the target gene encoding Ser19-Lys352 is expressed with a fusion design at the N-terminus. |
| Source: | Human Cells |
| Species: | Human |
| Molecular Mass: | Mol Mass: 105.7 kDa AP Mol Mass: 110-155 kDa, reducing conditions. |
| Protein length: | Ser19-Lys352 |
| Endotoxin: | Less than 0.001 ng/μg (0.01 EU/μg) as determined by LAL test. |
| Purity: | Greater than 95% as determined by reducing SDS-PAGE. |
| Storage: | Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days. Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
| Storage Buffer: | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
| Reconstitution: | Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Gene Name: | WNT3A wingless-type MMTV integration site family, member 3A [ Homo sapiens ] |
| Official Symbol: | WNT3A |
| Synonyms: | WNT3A; wingless-type MMTV integration site family, member 3A; protein Wnt-3a; MGC119418; MGC119419; MGC119420; |
| GeneID: | 89780 |
| mRNA Refseq: | NM_033131 |
| Protein Refseq: | NP_149122 |
| MIM: | 606359 |
| UniProt ID: | P56704 |
| Figure 1 |
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