Mouse Leukemia inhibitory factor（lif）is a secreted protein which belongs to the LIF/OSM family.LIF has been implicated in a many physiological processes including development, hematopoiesis, bone metabolism, and inflammation. it has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
| Short Name: |
Recombinant Mouse Lif Protein, low endotoxin |
| Cat#: |
EPLE-19M |
| Recombinant: |
E. coli |
| Abbr: |
Lif(Mouse) |
| Alias: |
LIF; leukemia inhibitory factor; d factor; differentiation-stimulating factor; |
| Type: |
L |
| similar: |
Lif |
| Product Overview: |
Recombinant Mouse Leukemia Inhibitory Factor is produced by our E.coli expression system and the target gene encoding Ser24-Phe203 is expressed. |
| Source: |
E.coli |
| Species: |
Mouse |
| Bio-activity: |
Measured by its ability to induce STAT reporter activity in 293F human embryonic kidney cells. The ED50 for this effect is 187 ng/mL. |
| Molecular Mass: |
Mol Mass: 19.9 kDa
AP Mol Mass: 18 kDa, reducing conditions. |
| Protein length: |
Ser24-Phe203 |
| Endotoxin: |
Less than 0.1 ng/μg (1 EU/μg) as determined by LAL test. |
| Purity: |
Greater than 95% as determined by reducing SDS-PAGE. |
| Storage: |
Lyophilized protein should be stored at < -20 centigrade, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7 centigrade for 2-7 days.
Aliquots of reconstituted samples are stable at < -20 centigrade for 3 months. |
| Storage Buffer: |
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4. |
| Reconstitution: |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 μg/mL. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Gene Name: |
Lif leukemia inhibitory factor [ Mus musculus ] |
| Official Symbol: |
Lif |
| Synonyms: |
LIF; leukemia inhibitory factor; d factor; differentiation-stimulating factor; |
| GeneID: |
16878 |
| mRNA Refseq: |
NM_001039537 |
| Protein Refseq: |
NP_001034626 |
| UniProt ID: |
P09056 |
| Figure 1 |
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| Figure 2 |
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